We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Blumeatin, 25mg
Product Description
Tiratricol is a metabolite of 3,3,5-triiodo-L-thyronine (Item No. ) and an agonist of the thyroid hormone receptors TRα and TRβ (EC50s = 1.81 and 4.13 nM, respectively, in reporter assays). In vivo, tiratricol (50 or 400 ng/g) stimulates cerebellar Purkinje cell dendritogenesis and cortical myelination in Mct8/Oatp1c1 double knockout mice. It reduces goiter induced by methimazole (Item No. ) in rats when administered at a dose of 25 μg per animal. Tiratricol also decreases toll-like receptor 2 (TLR2) levels and the phosphorylation of Akt and MAPK in HEK-Blue™ cells expressing human TLR2 and reduces liver tissue necrosis in a mouse model of hepatitis induced by concanavalin A (Item No. )..
WARNING This product is not for human or veterinary use.
Technical Information
- 3,3′,5-Triiodothyroacetic acid
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
Shipping & Storage Information
| SKU | CAYM-34809-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 34809-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 118024-26-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |