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Cayman Phellodendrine (Chloride), 1mg
List Price
$81.00
Your Price
$81.00
Cayman Phellodendrine (Chloride), 1mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-34802-1
MFG.PART:
34802-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Phellodendrine is an alkaloid that has been found in P. amurense and has diverse biological activities.1,2,3 It inhibits acetylcholinesterase (AChE) activity (IC50 = 36.51 µM) and scavenges ABTS (Item No. 27317) radicals in cell-free assays when used at concentrations ranging from 12.5 to 100 µM.2 Phellodendrine induces apoptosis in PANC-1 pancreatic cancer cells and reduces tumor growth in a PANC-1 mouse xenograft model.1 It inhibits the local graft versus host (GVH) reaction in irradiated mice receiving splenocyte grafts, indicating immunosuppressant activity, when administered at a dose of 20 mg/kg.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5,8,13,13aS-
CAS Number
104112-82-5
Molecular Formula
C20H24NO4 • Cl
Formula Weight
377.9
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- Ethanol: soluble
SMILES
C[N@+]12[C@](CC3=CC(O)=C(OC)C=C3C2)([H])C4=CC(O)=C(OC)C=C4CC1.[Cl-]
InChi Code
InChI=1S/C20H23NO4.ClH/c1-21-5-4-12-8-19(24-2)18(23)10-15(12)16(21)6-13-7-17(22)20(25-3)9-14(13)11-21;/h7-10,16H,4-6,11H2,1-3H3,(H-,22,23);1H/t16-,21-;/m0./s1
InChi Key
DGLDSNPMIYUWGN-ZOEDVAEJSA-N
Origin
Plant/Phellodendron chinense
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34802-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 34802-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 104112-82-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |