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Cayman Sildenafil Chlorosulfonyl, 5g
List Price
$319.00
Your Price
$319.00
Cayman Sildenafil Chlorosulfonyl, 5g - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-34760-5
MFG.PART:
34760-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles.,, SR 3335 is a selective inverse agonist of RORα, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation activity (IC50 = 480 nM). It is without effect on RORβ, RORγ, farnesoid X receptor, or liver X receptor α. SR 3335 evokes RORα-
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[4-[2,2,2- trifluoro-1- hydroxy-1- (trifluoro methyl)ethyl] phenyl]-2- thiophene sulfonamide
CAS Number
293753-05-6
Synonyms
- ML 176
Molecular Formula
C13H9F6NO3S2
Formula Weight
405.3
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMSO: 16 mg/ml
- Ethanol: 33 mg/ml
- Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
231 nm
SMILES
OC(C(F)(F)F)(C(F)(F)F)C1=CC=C(NS(C2=CC=CS2)(=O)=O)C=C1
InChi Code
InChI=1S/C13H9F6NO3S2/c14-12(15,16)11(21,13(17,18)19)8-3-5-9(6-4-8)20-25(22,23)10-2-1-7-24-10/h1-7,20-21H
InChi Key
LZWUNZRMANFRAO-UHFFFAOYSA-N
License
Sold under license from The Scripps Research Institute.
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34760-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 34760-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 139756-22-2 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |