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Cayman Cp 93,129 (Hydrochloride); Qty- 5; Size-5 Mg
Product Description
CP 93,129 is an agonist of the serotonin (5-HT) receptor subtype 5-HT1B.1 It selectively binds 5-HT1B over 5-HT1A, 5-HT1C, 5-HT1D, and 5-HT2 receptors (Kis = 0.0081, 1.5, 2.9, 1.1, and 7.2 µM, respectively). CP 93,129 (5.4 µM) inhibits potassium-induced GABA release from rat globus pallidus slices.2 It reverses akinesia in a rat model of Parkinson’s disease induced by reserpine (Item No. 16474) when administered intrapallidally at doses of 110 and 220 nmol/animal. CP 93,129 reduces food intake in rats when infused into the pons parabrachial nucleus or the paraventricular nucleus (PVN) of the hypothalamus (ED50s = 1 and 50 nmol/animal, respectively).3 It also reduces the frequency of pursuits, tail rattles, threats, and attack bites in a resident-intruder test in mice.4
WARNING This product is not for human or veterinary use.
Technical Information
- DMSO: 100 mM
- Water: 100 mM
Shipping & Storage Information
| SKU | CAYM-34548-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 34548-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 879089-64-2 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |