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Cayman 93-O17o, 10mg
List Price
$192.00
Your Price
$192.00
Cayman 93-O17o, 10mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-34366-10
MFG.PART:
34366-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Aflutinib is an inhibitor of mutant EGFRs. It is selective for EGFRL858R, EGFRG719X, EGFRL858R, EGFRL861A, and EGFRT790M mutant EGFRs over wild-type EGFR. Aflutinib (10 and 30 mg/kg) reduces tumor growth in an EGFRL858R and EGFRT790M-expressing LU1868 non-small cell lung cancer (NSCLC) patient-derived xenograft (PDX) mouse model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2-[[2- (dimethyl amino)ethyl] methylamino]- 5-[[4-(1- methyl-1H- indol-3-yl)-2- pyrimidinyl] amino]-6- (2,2,2-tri fluoroethoxy)- 3-pyridinyl]- 2-propenamide, monomethane sulfonate
CAS Number
2130958-55-1
Synonyms
- AST2818
Molecular Formula
C28H31F3N8O2 • CH3SO3H
Formula Weight
664.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- Chloroform: 10 mg/ml
- DMF: slightly soluble
- DMSO: slightly soluble
λmax
267, 332 nm
SMILES
O=C(NC1=CC(NC2=NC(C3=CN(C)C4=C3C=CC=C4)=CC=N2)=C(OCC(F)(F)F)N=C1N(CCN(C)C)C)C=C.O=S(O)(C)=O
InChi Code
InChI=1S/C28H31F3N8O2.CH4O3S/c1-6-24(40)33-21-15-22(26(41-17-28(29,30)31)36-25(21)38(4)14-13-37(2)3)35-27-32-12-11-20(34-27)19-16-39(5)23-10-8-7-9-18(19)23;1-5(2,3)4/h6-12,15-16H,1,13-14,17H2,2-5H3,(H,33,40)(H,32,34,35);1H3,(H,2,3,4)
InChi Key
WDPGHXINXNBHAS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-34366-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 34366-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 2227214-78-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |