Cayman Mdk35833, 1g

Name: Cayman Mdk35833, 1g
SKU: CAYM-34332-1
Price: 380.00 USD

List Price $380.00 Your Price $380.00

Cayman Mdk35833, 1g - CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-34332-1

MFG.PART: 34332-1

UNSPSC: 12352200

Manufacturer: Cayman

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Description

Product Description

PKI PKA Inhibitor (5-24) is a synthetic peptide inhibitor of PKA (cAMP-dependent protein kinase) (K_i = 2.3 nM) derived from the active site of the skeletal muscle inhibitor protein. It mimics the protein substrate by binding to the catalytic site through the arginine-cluster basic subsite. The prominent enzyme-substrate interaction site occurs where PKA catalytic subunit residues Tyr²³⁵ and Phe²³⁹ form a sandwich-like structure with residue Phe¹⁰ of PKI (5-24).

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

L-threonyl-L-threonyl-L-tyrosyl-L-alanyl-L-α-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-serylglycyl-L-arginyl-L-threonylglycyl-larginyl-L-aspartic acid, 2,2,2-trifluoroacetate salt

Synonyms

PKI (5-24)
Protein Kinase A Inhibitor (5-24)

Molecular Formula

C₉₄H₁₄₈N₃₂O₃₁ • XCF₃COOH

Formula Weight

2222.4

Purity

≥95%

Formulation

A crystalline solid

Solubility

DMSO: 1 mg/ml
PBS (pH 7.2): 2 mg/ml

SMILES

[H]N[C@]([C@@H](C)O)([H])C(N[C@]([C@@H](C)O)([H])C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@H](C(N[C@@H](CO)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@]([C@@H](C)O)([H])C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@H](C(N[C@H](C(O)=O)CC(O)=O)=O)CC1=CN=CN1)=O)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)CC2=CC=CC=C2)=O)CC(O)=O)=O)C)=O)CC3=CC=C(O)C=C3)=O)=O.OC(C(F)(F)F)=O

InChi Code

InChI=1S/C94H148N32O31.C2HF3O2/c1-11-42(3)70(124-85(150)58(31-50-19-14-13-15-20-50)117-84(149)61(35-67(135)136)116-74(139)44(5)110-81(146)57(32-51-24-26-53(131)27-25-51)119-90(155)73(49(10)130)126-86(151)69(96)47(8)128)88(153)112-45(6)75(140)122-63(40-127)77(142)107-38-65(133)114-55(22-17-29-105-93(99)100)80(145)125-72(48(9)129)87(152)108-39-66(134)113-54(21-16-28-104-92(97)98)78(143)115-56(23-18-30-106-94(101)102)79(144)118-60(34-64(95)132)82(147)111-46(7)76(141)123-71(43(4)12-2)89(154)120-59(33-52-37-103-41-109-52)83(148)121-62(91(156)157)36-68(137)138;3-2(4,5)1(6)7/h13-15,19-20,24-27,37,41-49,54-63,69-73,127-131H,11-12,16-18,21-23,28-36,38-40,96H2,1-10H3,(H2,95,132)(H,103,109)(H,107,142)(H,108,152)(H,110,146)(H,111,147)(H,112,153)(H,113,134)(H,114,133)(H,115,143)(H,116,139)(H,117,149)(H,118,144)(H,119,155)(H,120,154)(H,121,148)(H,122,140)(H,123,141)(H,124,150)(H,125,145)(H,126,151)(H,135,136)(H,137,138)(H,156,157)(H4,97,98,104)(H4,99,100,105)(H4,101,102,106);(H,6,7)/t42-,43-,44-,45-,46-,47+,48+,49+,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,69-,70-,71-,72-,73-;/m0./s1

InChi Key

CRACXDGIDXNBAQ-AYVQDJQPSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 4 years

Specifications

More Information
SKU	CAYM-34332-1
Featured	No
Supplier Part Number	34332-1
UM	EA
UNSPSC	12352200
Manufacturer Name	Cayman
MSDS URL	Click here
Temperature	-20
Refrigerated-Frozen	Refrigerated
CountryOfOrigin	China
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	2
Hazardous	N
CAS Number	1016535-83-3
Energy Star	No
Green	No
ACT Ecolabel	No
Controlled	N

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NETA PART NO.	Quantity

Cayman Mdk35833, 1g

Product Description

Technical Information

Shipping & Storage Information

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