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Cayman 1,2-Dioleoyl-Sn-Glycero-3-Pa (Sodium Salt), 5mg
List Price
$62.00
Your Price
$62.00
Cayman 1,2-Dioleoyl-Sn-Glycero-3-Pa (Sodium Salt), 5mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-34274-5
MFG.PART:
34274-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Resolvin conjugate in tissue regeneration 1 (RCTR1) is a specialized pro-resolving mediator (SPM) biosynthesized from docosahexaenoic acid (DHA; Item No. ) by isolated human macrophages and apoptotic polymorphonuclear (PMN) neutrophils. It has been found in human spleen and bone marrow. RCTR1 is produced via lipoxygenase-mediated oxidation of DHA to 7(S)-8-epoxy-17(S)-HDHA, which is conjugated to glutathione.,, RCTR1 (10 nM) increases phagocytosis of E. coli or apoptotic neutrophils in isolated human monocyte-derived macrophages. It decreases chemotaxis induced by leukotriene B4 (LTB4; Item No. ) in isolated human neutrophils when used at a concentration of 10 nM. RCTR1 (1 and 10 nM) accelerates tissue regeneration in planaria. Intraperitoneal administration of RCTR1 (100 ng/animal) shortens the inflammatory resolution period and decreases inflammatory exudate neutrophil infiltration in a mouse model of E. coli-induced peritonitis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(4Z,7S,8R,9E,
CAS Number
2095607-49-9
Synonyms
- Resolvin Glutathione Conjugate in Tissue Regeneration 1
- Resolvin Sulfido Conjugate 1
Molecular Formula
C32H47N3O10S
Formula Weight
665.8
Purity
≥95%
Formulation
A solution in ethanol
Solubility
- Ethanol: >0.5 mg/ml
SMILES
O[C@@H](C/C=C\CCC(O)=O)[C@H](SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O)/C=C/C=C/C=C\C=C\[C@@H](O)C/C=C\CC
InChi Code
InChI=1S/C32H47N3O10S/c1-2-3-9-14-23(36)15-10-6-4-5-7-12-17-27(26(37)16-11-8-13-18-29(39)40)46-22-25(31(43)34-21-30(41)42)35-28(38)20-19-24(33)32(44)45/h3-12,15,17,23-27,36-37H,2,13-14,16,18-22,33H2,1H3,(H,34,43)(H,35,38)(H,39,40)(H,41,42)(H,44,45)/b6-4-,7-5+,9-3-,11-8-,15-10+,17-12+/t23-,24?,25-,26-,27+/m0/s1
InChi Key
ISXZTIZZJJNZGD-GOIMJDBFSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-34274-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 34274-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 108392-02-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |