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Cayman Indapamide-13c-D3; Qty- 5; Size-5 Mg
Product Description
Deoxycholic acid (DCA) is a secondary bile acid that is formed via microbial transformation of cholic acid (Item No. ) in the colon. It can be conjugated to glycine or taurine (Item No. ) to produce glycodeoxycholic acid (GDCA; Item No. ) or taurodeoxycholic acid (TDCA; Item No. ), respectively, in hepatocytes.,, DCA (0.2% v/v) inhibits spore germination induced by taurocholic acid (TCA; Item No. ) in seven C. difficile strains, as well as inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells when used at a concentration of 0.02% v/v. It inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells when used at a concentration of 200 µM. Fecal and intestinal tissue levels of DCA are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet. Increased serum DCA levels have been found in patients with colorectal cancer.
WARNING This product is not for human or veterinary use.
Technical Information
- DCA
- Sodium Deoxycholate
- DMF: 5 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 15 mg/ml
- PBS (pH 7.2): 1 mg/ml
Shipping & Storage Information
| SKU | CAYM-34244-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 34244-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |