Cayman Chlorzoxazone-D3, 500ug

Name: Cayman Chlorzoxazone-D3, 500ug
SKU: CAYM-34237-500
Price: 144.00 USD

List Price $144.00 Your Price $144.00

Cayman Chlorzoxazone-D3, 500ug - CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-34237-500

MFG.PART: 34237-500

UNSPSC: 12352200

Manufacturer: Cayman

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Description

Product Description

Cyclopamine is a natural steroidal alkaloid that inhibits signaling through the hedgehog pathway at the level of the pathway activator Smoothened.^, By altering gene expression in this signaling sequence, cyclopamine induces defects in morphogenesis, first observed in chicks and sheep as cyclopia. As a readout of action, cyclopamine inhibits hedgehog-dependent expression of Pax7 with an IC₅₀ value of 24 nM. Although teratogenic during development, cyclopamine has potential applications in the treatment of cancer.^,,

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

(2R,3S,3R,3aS,6S,6aS,6bS,7aR,11aS,11bR)-1,2,3,3a,4,4,5,6,6,6a,6b,7,7,7a,8,11,11a,11b-octadecahydro-3,6,10,11b-tetramethyl-spiro[9H-benzo[a]fluorene-9,2(3H)-furo[3,2-b]pyridin]-3-ol

CAS Number

4449-51-8

Synonyms

11-Deoxojervine
Jervine

Molecular Formula

C₂₇H₄₁NO₂

Formula Weight

411.6

Purity

≥95%

Formulation

A crystalline solid

Solubility

DMF: 2 mg/ml
Ethanol: 10 mg/ml
Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml

SMILES

O[C@H](C1)CC[C@@]2(C)C1=CC[C@]3([H])[C@]2([H])CC4=C(C)[C@]5([C@H](C)[C@@](NC[C@@H](C)C6)([H])[C@]6([H])O5)CC[C@@]34[H]

InChi Code

InChI=1S/C27H41NO2/c1-15-11-24-25(28-14-15)17(3)27(30-24)10-8-20-21-6-5-18-12-19(29)7-9-26(18,4)23(21)13-22(20)16(27)2/h5,15,17,19-21,23-25,28-29H,6-14H2,1-4H3/t15-,17+,19-,20-,21-,23-,24+,25-,26-,27-/m0/s1

InChi Key

QASFUMOKHFSJGL-LAFRSMQTSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 4 years

Specifications

More Information
SKU	CAYM-34237-500
Featured	No
Supplier Part Number	34237-500
UM	EA
UNSPSC	12352200
Manufacturer Name	Cayman
MSDS URL	Click here
Temperature	-20
Refrigerated-Frozen	Refrigerated
CountryOfOrigin	Canada
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	2
Hazardous	N
CAS Number	1185173-60-7
Energy Star	No
Green	No
ACT Ecolabel	No
Controlled	N

Provide Content Correction

NETA PART NO.	Quantity

Cayman Chlorzoxazone-D3, 500ug

Product Description

Technical Information

Shipping & Storage Information

Product Title