We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Pf-998425, 4--2-(Trifluoromet
List Price
$98.00
Your Price
$98.00
Cayman Pf-998425, 4-[(1r,2r)-2-Hydroxycyclohexyl]-2-(Trifluoromethyl)-Benzonitrile, 5 Mg - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-31442-5
MFG.PART:
31442-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid (Item No. ) at the sn-1 position and 15(S)-HpETE (Item No. ) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE (SAPE; Item No. ) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
[S-[R*,S*- (E,Z,Z,Z)]]- 15-hydro peroxy- 5,8,11,13- eicosatet raenoic acid, 2-[[(2- aminoethoxy) hydroxy phosphinyl] oxy]-1-[[(1- oxooctadecyl) oxy]methyl] ethyl ester
CAS Number
154436-49-4
Synonyms
- 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-phosphoethanolamine
- 15(S)-HpETE-SAPE
- 15(S)-hydroperoxyeicostetraenoic acid-SAPE
Molecular Formula
C43H78NO10P
Formula Weight
800.1
Purity
≥90%
Formulation
A solution in ethanol
Solubility
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
λmax
237 nm
SMILES
O=C(CCCCCCCCCCCCCCCCC)OC[C@@H](OC(CCC/C=C\C/C=C\C/C=C\C=C\[C@@H](OO)CCCCC)=O)COP(OCCN)(O)=O
InChi Code
InChI=1S/C43H78NO10P/c1-3-5-7-8-9-10-11-12-13-14-17-20-23-26-30-34-42(45)50-38-41(39-52-55(48,49)51-37-36-44)53-43(46)35-31-27-24-21-18-15-16-19-22-25-29-33-40(54-47)32-28-6-4-2/h15-16,21-22,24-25,29,33,40-41,47H,3-14,17-20,23,26-28,30-32,34-39,44H2,1-2H3,(H,48,49)/b16-15-,24-21-,25-22-,33-29+/t40?,41-/m1/s1
InChi Key
ILISYDMFRZNALR-LWZJHDPASA-N
Side Chain Carbon Sum
38:4
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-31442-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 31442-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1076225-27-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |