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Cayman Zidebactam, 10mg
Product Description
Zidebactam is a penicillin-binding protein 2 (PBP2) inhibitor and β-lactam antibiotic enhancer.1 It inhibits P. aeruginosa PBP2 (IC50 = 0.26 µg/ml) and is selective for PBP2 over PBP1a, -1b, -3, -4, and -5/6 (IC50s = >4 µg/ml for all). Zidebactam enhances the bactericidal activity of cefepime (Item No. 23633) against multidrug-resistant strains of P. aeruginosa, as well as against E. coli, Klebsiella, Enterobacter, S. marcescens, and A. baumannii.2 In vivo, zidebactam enhances cefepime-induced reductions in bacterial loads in mouse models of K. pneumoniae-induced peritonitis and thigh infection.3 Formulations containing zidebactam in combination with cefepime have been used in the treatment of various bacterial infections.
WARNING This product is not for human or veterinary use.
Technical Information
- WCK-5107
- Water: soluble
Shipping & Storage Information
| SKU | CAYM-30701-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 30701-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1436861-97-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |