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Cayman Cilnidipine; Purity- Greater Than Or Equal To 98%; Size- 5
List Price
$370.00
Your Price
$370.00
Cayman Cilnidipine; Purity- Greater Than Or Equal To 98%; Size- 5 G; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-26080-5
MFG.PART:
26080-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
GPR119, a glucose-dependent insulinotropic receptor, is a G protein-coupled receptor that is expressed in pancreatic β-cells and intestinal L-cells. Activation of GPR119 by the endogenous ligands lyso-phosphatidylcholine (Item No. and oleoyl ethanolamide (Item No. ) increases intracellular cAMP levels and promotes glucose-stimulated insulin secretion., APD668 is a potent agonist of GPR119 (EC50s = 2.7 and 33 nM for human and rat forms, respectively). Chronic dosing with APD668 in Zucker diabetic fatty rats over several weeks significantly reduces blood glucose and glycated hemoglobin levels.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[[1-[2-
CAS Number
832714-46-2
Synonyms
- JNJ-28630368
Molecular Formula
C21H24FN5O5S
Formula Weight
477.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMF:PBS (pH 7.2) (1:8): 0.1 mg/ml
- DMSO: 20 mg/ml
λmax
242, 276 nm
SMILES
CC(C)OC(N1CCC(OC2=NC=NC3=C2C=NN3C4=CC=C(S(C)(=O)=O)C=C4F)CC1)=O
InChi Code
InChI=1S/C21H24FN5O5S/c1-13(2)31-21(28)26-8-6-14(7-9-26)32-20-16-11-25-27(19(16)23-12-24-20)18-5-4-15(10-17(18)22)33(3,29)30/h4-5,10-14H,6-9H2,1-3H3
InChi Key
XTRUQJBVQBUKSQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-26080-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 26080-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 132203-70-4 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |