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Cayman Prlx-93936; Purity- Greater Than Or Equal To 98%; Size- 5
List Price
$233.00
Your Price
$233.00
Cayman Prlx-93936; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25631-5
MFG.PART:
25631-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CYC-116 is a potent Aurora kinase inhibitor exhibiting Ki values of 8.0 and 9.2 nM for Aurora kinases A and B, respectively. It is significantly less potent against a panel of cyclin-dependent kinases and other related kinases, with the exception of Flt-3 (Ki = 44 nM). CYC-116 exhibits broad-spectrum antiproliferative activity against a panel of human cancer cell lines with a mean IC50 value of 0.54 µM (range = 0.09 – 1.6 µM). It is orally bioavailable and inhibits the growth of human tumor xenografts in mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(2-amino-4-
CAS Number
693228-63-6
Molecular Formula
C18H20N6OS
Formula Weight
368.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 1.25 mg/ml
- DMSO: 10 mg/ml
- DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
λmax
295, 337 nm
SMILES
CC(N=C(N)S1)=C1C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2
InChi Code
InChI=1S/C18H20N6OS/c1-12-16(26-17(19)21-12)15-6-7-20-18(23-15)22-13-2-4-14(5-3-13)24-8-10-25-11-9-24/h2-7H,8-11H2,1H3,(H2,19,21)(H,20,22,23)
InChi Key
GPSZYOIFQZPWEJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25631-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 25631-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 903499-49-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |