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Cayman Ruscogenin; Purity- Greater Than Or Equal To 98%; Size- 25
Product Description
Epothilones are microtubule-stabilizing agents with potential anti-neoplastic actions.,, They are natural macrolides that have high potency in both taxane-sensitive and taxane-resistant models., Epothilone D is a desoxy form of epothilone B (Item No. ) that inhibits the growth of a variety of cancer cells both in vitro (IC50 values range from 0.97 to 21 nM) and in mice., Epothilone D is brain penetrant and reduces neurodegeneration in aged tau transgenic mice., Effects include improved axonal transport, decreased tau neuropathology, and reduced hippocampal neuron loss., Epothilone D also rescues microtubule defects and attenuates nigrostriatal degeneration in a mouse model of Parkinson’s disease.
WARNING This product is not for human or veterinary use.
Technical Information
- Desoxyepothilone B
- NSC 73147
- DMSO: Soluble
- Ethanol: Soluble
Shipping & Storage Information
| SKU | CAYM-25217-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 25217-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 472-11-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |