Cayman Parathyroid Hormone (1-34) (Human) (Trifluoroacetate Salt)

Dolastatin 15 is a peptide that has been found in D. auricularia and has anticancer activity.^,, It induces cell cycle arrest at the G₂/M phase and inhibits proliferation of JVM-2 and EHEB human B cell leukemia cells when used at a concentration of 1 nM. Dolastatin 15 also inhibits proliferation of RPMI-8826, U266, and IM-9 human multiple myeloma cells (IC₅₀s = 0.5-1 nM), as well as a panel of colon and ovarian cancer cell lines (IC₅₀s = 0.031-1.8 nM).^, It reduces tumor growth in a CH1 mouse xenograft model when administered at a dose of 5.25 mg/kg per day.

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