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Cayman Orteronel; Purity- Greater Than Or Equal To 98%; Size- 5 M
List Price
$178.00
Your Price
$178.00
Cayman Orteronel; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-24191-5
MFG.PART:
24191-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CHR-6494 is a haspin protein kinase inhibitor (IC50 = 2 nM) selective over 27 other protein kinases, including Aurora B kinase (IC50 > 1 µM). Haspin is a kinase necessary for mitosis that selectively phosphorylates histone 3 at the threonine 3 residue (H3T3ph). CHR-6494 decreases phosphorylation of H3T3 and arrests the cell cycle in the G2/M phase, which leads to apoptosis. It showed promising results in a xenograft tumor model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-(1H-indazol-
CAS Number
1333377-65-3
Molecular Formula
C16H16N6
Formula Weight
292.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 12.5 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS(pH 7.2) (1:4): 0.2 mg/ml
- Ethanol: 0.25 mg/ml
λmax
213, 252, 335 nm
SMILES
CCCNC(C=C1)=NN2C1=NC=C2C3=CC(C=NN4)=C4C=C3
InChi Code
InChI=1S/C16H16N6/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20)
InChi Key
CZZCAOGIEGXMBZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24191-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 24191-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 566939-85-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |