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Cayman Tetromycin B; Purity- Greater Than Or Equal To 99%; Size-
List Price
$267.75
Your Price
$267.75
Cayman Tetromycin B; Purity- Greater Than Or Equal To 99%; Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-23766-500
MFG.PART:
23766-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Nedocromil is a mast cell stabilizer. It inhibits IgE-induced histamine release from rat peritoneal mast cells cocultured with 3T3 cells (MC/3T3) and preincubated with IL-2 when used at a concentration of 10 µM in acute (1 hour) and chronic (5 days) assays. Nedocromil prevents early- and late-phase bronchoconstriction in a guinea pig model of asthma induced by ovalbumin. It also prevents conjunctival edema and erythema and reduces mast cell degranulation in a rat model of conjunctivitis when administered intravenously at a dose of 2 mg/kg. Formulations containing nedocromil have been used in the treatment of allergic conjunctivitis and asthma.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
9-ethyl-6,9- dihydro-4,6- dioxo-10-propyl- 4H-pyrano[3,2-g] quinoline-2,8- dicarboxylic acid, di sodium salt
CAS Number
69049-74-7
Molecular Formula
C19H15NO7 • 2Na
Formula Weight
415.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 20 mg/ml
- Ethanol: 30 mg/ml
- PBS (pH 7.2): 1 mg/ml
λmax
251, 286, 339, 372 nm
SMILES
O=C(C=C(C([O-])=O)O1)C(C1=C2CCC)=CC3=C2N(CC)C(C([O-])=O)=CC3=O.[Na+].[Na+]
InChi Code
InChI=1S/C19H17NO7.2Na/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11;;/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26);;/q;2*+1/p-2
InChi Key
JQEKDNLKIVGXAU-UHFFFAOYSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-23766-500 |
|---|---|
| Featured | No |
| Supplier Part Number | 23766-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 180027-84-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |