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Cayman Hydroxy Bosentan; Purity- Greater Than Or Equal To 98%; Si
List Price
$217.00
Your Price
$217.00
Cayman Hydroxy Bosentan; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22366-1
MFG.PART:
22366-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Hydroxy bosentan is an active phase I metabolite of bosentan (Item No. ) produced by the cytochrome P450 isoforms CYP3A4 and CYP2C9., Bosentan is an antagonist of the endothelin receptors type A (Ki = 6.5 nM) and type B (Ki = 340 nM)., Up to 20% of the activity of bosentan may be due to the action of hydroxy bosentan because even though it has a lower affinity for endothelin receptors, its concentration is 3-fold higher in plasma.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(2-hydroxy-
CAS Number
253688-60-7
Synonyms
- Ro 48-5033
- Ro 48-8634
Molecular Formula
C27H29N5O7S
Formula Weight
567.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: soluble
SMILES
COC1=CC=CC=C1OC2=C(NS(C3=CC=C(C(C)(CO)C)C=C3)(=O)=O)N=C(C4=NC=CC=N4)N=C2OCCO
InChi Code
InChI=1S/C27H29N5O7S/c1-27(2,17-34)18-9-11-19(12-10-18)40(35,36)32-23-22(39-21-8-5-4-7-20(21)37-3)26(38-16-15-33)31-25(30-23)24-28-13-6-14-29-24/h4-14,33-34H,15-17H2,1-3H3,(H,30,31,32)
InChi Key
FAJQMBCLPZWTQJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22366-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 22366-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 253688-60-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |