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Cayman Dimethylenastron; Purity- Greater Than Or Equal To 98%; Si
List Price
$32.00
Your Price
$32.00
Cayman Dimethylenastron; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22357-1
MFG.PART:
22357-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Dimethylenastron is an inhibitor of the mitotic kinesin Eg5 (IC50 = 200 nM in an ATPase assay). It is selective for Eg5 over other kinesin subfamilies from four different organisms. Dimethylenastron induces accumulation of HeLa cells in the G2/M phase (75% at a concentration of 1 μM). It inhibits spindle formation and induces radial arrangement of chromosomes in Xenopus oocytes. Dimethylenastron inhibits migration and growth of PANC-1 pancreatic cancer cells in a concentration-dependent manner. Dimethylenastron also inhibits angiogenesis and induces severe circulation defects in zebrafish embryos.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,3,4,6,7,8-
CAS Number
863774-58-7
Molecular Formula
C16H18N2O2S
Formula Weight
302.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/ml
- DMSO: 5 mg/ml
- Ethanol: 1 mg/ml
λmax
324 nm
SMILES
O=C1CC(C)(C)CC2=C1C(C3=CC(O)=CC=C3)NC(N2)=S
InChi Code
InChI=1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21)
InChi Key
RUOOPLOUUAYNPY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22357-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 22357-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 863774-58-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |