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Cayman Nifurtimox; Purity- Greater Than Or Equal To 98%; Size- 5
List Price
$116.00
Your Price
$116.00
Cayman Nifurtimox; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21784-5
MFG.PART:
21784-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Nifurtimox is an antiprotozoal agent.1 It is active against Taluahuén, LQ, and Brener strains of T. cruzi epimastigotes with IC50 values of 9.91, 12.28, and 10.44 µM, respectively. Nifurtimox inhibits clonogenic growth of HCT116, H838, C33A, LN18, KNS42, MDA-MB-231, and FaDu tumor cells under hypoxic conditions.2 It reduces parasitemia and increases survival in a mouse model of T. cruzi infection when administered at doses of 10 and 40 mg/kg per day.3 Dietary administration of nifurtimox (150 mg/kg per day for 28 days) increases tumor cell apoptosis and reduces tumor growth in an SMS-KCNR mouse xenograft model.4
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-methyl-N-[(
CAS Number
23256-30-6
Synonyms
- BAY-2502
- BAY-A-2502
Molecular Formula
C10H13N3O5S
Formula Weight
287.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 20 mg/ml
λmax
275, 399 nm
SMILES
CC1CS(CCN1/N=C/C2=CC=C([N+]([O-])=O)O2)(=O)=O
InChi Code
InChI=1S/C10H13N3O5S/c1-8-7-19(16,17)5-4-12(8)11-6-9-2-3-10(18-9)13(14)15/h2-3,6,8H,4-5,7H2,1H3/b11-6+
InChi Key
ARFHIAQFJWUCFH-IZZDOVSWSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21784-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 21784-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 23256-30-6 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |