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Cayman Cnx-774; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
List Price
$120.00
Your Price
$120.00
Cayman Cnx-774; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21475-5
MFG.PART:
21475-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
2-O-Galloylhyperin is a natural flavonoid that has been found in P. incarnata and has diverse biological activities, including antioxidant, anti-inflammatory, hepatoprotective, and transporter-inhibiting properties.,, It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. ) and ABTS (Item No. ) radicals (IC50s = 3 and 3.5 μM, respectively). It also inhibits human organic anion transporting polypeptide 1B1 (OATP1B1; IC50 = 19 μM in HEK293 cells). 2-O-Galloylhyperin (15 μM) decreases LPS-induced IL-6 and TNF-α cytokine production from mouse RAW 264.7 macrophages. It also decreases LPS-induced mortality and liver damage in a mouse model of septic shock when administered at a dose of 50 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-(3,4-dihydroxy
CAS Number
53209-27-1
Synonyms
- Hyperin-2-Gallate
Molecular Formula
C28H24O16
Formula Weight
616.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
260, 360 nm
SMILES
OC1=CC(O)=C2C(OC(C3=CC=C(O)C(O)=C3)=C(O[C@H]4[C@H](OC(C5=CC(O)=C(O)C(O)=C5)=O)[C@@H](O)[C@@H](O)[C@@H](CO)O4)C2=O)=C1
InChi Code
InChI=1S/C28H24O16/c29-8-18-21(37)23(39)26(43-27(40)10-4-15(34)20(36)16(35)5-10)28(42-18)44-25-22(38)19-14(33)6-11(30)7-17(19)41-24(25)9-1-2-12(31)13(32)3-9/h1-7,18,21,23,26,28-37,39H,8H2/t18-,21+,23+,26-,28+/m1/s1
InChi Key
PXGWEUQZDRUMRE-UNZYZCBSSA-N
Origin
Plant/Pyrola calliantha
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21475-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 21475-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1202759-32-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |