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Cayman Tnp; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
List Price
$143.00
Your Price
$143.00
Cayman Tnp; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-21189-5
MFG.PART:
21189-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
AC-186 is a non-steroidal estrogen receptor β (ERβ) agonist (EC50 = 6 nM in a functional assay). It is selective for ERβ over ERα (EC50 = 5,000 nM). AC-186 (10 mg/kg) reduces dopaminergic neuronal loss in the substantia nigra, improves novel object recognition, and improves motor performance in male, but not female, rats in a model of Parkinson’s disease induced by 6-OHDA (Item No. ). It reduces tactile allodynia in male, but not female or female ovariectomized, rats in a model of spinal nerve ligation-induced neuropathic pain. AC-186 (10 and 30 mg/kg) also reduces tactile allodynia in male rats in a model of neuropathic pain induced by paclitaxel (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-[4,4-difluoro-
CAS Number
1421854-16-1
Molecular Formula
C18H17F3O
Formula Weight
306.3
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: soluble
- Ethanol: soluble
λmax
230 nm
SMILES
FC1(F)CCC(C2=CC=C(O)C=C2)(C3=CC=CC=C3F)CC1
InChi Code
InChI=1S/C18H17F3O/c19-16-4-2-1-3-15(16)17(9-11-18(20,21)12-10-17)13-5-7-14(22)8-6-13/h1-8,22H,9-12H2
InChi Key
HSMUKSLNDJOZQG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-21189-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 21189-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 519178-28-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |