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Cayman Ginsenoside Rg2; Purity- Greater Than Or Equal To 98%; Siz
List Price
$191.00
Your Price
$191.00
Cayman Ginsenoside Rg2; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-15331-5
MFG.PART:
15331-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Glutamate, the major excitatory neurotransmitter in the CNS, activates eight known subtypes of metabotropic glutamate receptors (mGluRs). Highly selective modulators designed to act at allosteric sites on certain mGluR subtypes are being developed to preferentially regulate subtype-specific, glutamate-induced receptor activation. VU0483605 is a selective positive allosteric modulator (PAM) of mGluR1, displaying EC50 values of 0.39 and 0.36 μM at human and rat receptors, respectively, and no activity as a mGlu4 PAM (EC50 >10 μM). It has been shown to potentiate a response to glutamate in wild-type cell lines stably expressing mGlu1 and to partially restore the reduction in glutamate-mediated calcium signaling in a mutant cell model of schizophrenia.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-chloro-N-[3-chloro-4-(4-chloro-1,3-dihydro-1,3-dioxo-2H-isoindol-2-yl)phenyl]-2-pyridinecarboxamide
CAS Number
1623101-11-0
Molecular Formula
C20H10Cl3N3O3
Formula Weight
446.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/ml
- DMSO: 20 mg/ml
- DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml
λmax
219, 280 nm
SMILES
O=C1N(C2=CC=C(NC(C3=C(Cl)C=CC=N3)=O)C=C2Cl)C(C4=CC=CC(Cl)=C41)=O
InChi Code
InChI=1S/C20H10Cl3N3O3/c21-12-4-1-3-11-16(12)20(29)26(19(11)28)15-7-6-10(9-14(15)23)25-18(27)17-13(22)5-2-8-24-17/h1-9H,(H,25,27)
InChi Key
HJQXPBKPTGWZCF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-15331-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 15331-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United Kingdom |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 52286-74-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |