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Cayman Daunorubicin (Hydrochloride); Purity- Greater Than Or Equa
List Price
$190.00
Your Price
$190.00
Cayman Daunorubicin (Hydrochloride); Purity- Greater Than Or Equal To 98%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-14159-50
MFG.PART:
14159-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Daunorubicin is an antitumor antibiotic.1 At 0.2-1μM, daunorubicin induces apoptosis in mature monocytic U937 and myelocytic HL-60 acute myeloid leukemia (AML) cells. However, immature AML cells (CD 34+-KG1a, -KG1, or -HEL cells) appear resistant to apoptosis at similar concentrations.1 In mature AML cells, daunorubicin has been shown to trigger a reactive oxygen species-dependent sphingomyelin-ceramide pathway that activates the MEKK1-SEK1-JNK cascade leading to enhanced DNA binding activity of the transcription factor AP-1.1,2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
8S-
CAS Number
23541-50-6
Synonyms
- NDC 0082-
4155 - Ondena
- RP 13057
Molecular Formula
C27H29NO10 • HCl
Formula Weight
564.0
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 20 mg/ml
- DMSO: 10 mg/ml
- Ethanol: 0.5 mg/ml
- PBS (pH 7.2): 10 mg/ml
λmax
234, 251, 288, 480 nm
SMILES
COC1=C(C(C(C(O)=C([C@@H](O[C@@]2([H])C[C@H](N)[C@H](O)[C@H](C)O2)C[C@@](C(C)=O)(O)C3)C3=C4O)=C4C5=O)=O)C5=CC=C1.Cl
InChi Code
InChI=1S/C27H29NO10.ClH/c1-10-22(30)14(28)7-17(37-10)38-16-9-27(35,11(2)29)8-13-19(16)26(34)21-20(24(13)32)23(31)12-5-4-6-15(36-3)18(12)25(21)33;/h4-6,10,14,16-17,22,30,32,34-35H,7-9,28H2,1-3H3;1H/t10-,14-,16-,17-,22+,27-;/m0./s1
InChi Key
GUGHGUXZJWAIAS-QQYBVWGSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14159-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 14159-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 23541-50-6 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |