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Cayman Ingenol; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
List Price
$249.00
Your Price
$249.00
Cayman Ingenol; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-14031-5
MFG.PART:
14031-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Sitamaquine is an antileishmanial agent. It is active against L. donovani, L. infantum, L. mexicana, L. braziliensis, and L. tropica (EC50s = 9.5-19.8 µM). It inhibits mitochondrial complex II, also known as succinate dehydrogenase (SDH), in a cell-free assay when used at concentrations ranging from 10 to 200 µM. Sitamaquine (100 µM) increases intracellular levels of reactive oxygen species (ROS) and decreases intracellular ATP levels, as well as induces phosphatidylserine externalization, chromatin fragmentation, and depolarization of the mitochondrial membrane potential, markers of apoptosis, in L. donovani promastigotes.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N1,N1-
CAS Number
1019640-33-5
Synonyms
- WR-6026
Molecular Formula
C21H33N3O • C7H8O3S
Formula Weight
515.7
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 30 mg/ml
SMILES
O=S(O)(C1=CC=C(C)C=C1)=O.COC2=CC3=C(C)C=CN=C3C(NCCCCCCN(CC)CC)=C2
InChi Code
InChI=1S/C21H33N3O.C7H8O3S/c1-5-24(6-2)14-10-8-7-9-12-22-20-16-18(25-4)15-19-17(3)11-13-23-21(19)20;1-6-2-4-7(5-3-6)11(8,9)10/h11,13,15-16,22H,5-10,12,14H2,1-4H3;2-5H,1H3,(H,8,9,10)
InChi Key
LOBPWLFCZDGYKW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-14031-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 14031-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 30220-46-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |