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Cayman Dimethocaine (Hydrochloride); Purity- Greater Than Or Equa
Product Description
Oxfenicine is an inhibitor of carnitine palmitoyltransferase 1 (CPT1) and a prodrug form of 4-hydroxyphenylglyoxylic acid., Oxfenicine is transaminated to 4-hydroxyphenylglyoxylic acid by branched-chain amino acid aminotransferase in rat heart homogenates. It inhibits fatty acid oxidation and increases carbohydrate oxidation in isolated rat hearts perfused with palmitate (Item No. ), glucose, and insulin. Oxfenicine increases the ex vivo activity of cardiac pyruvate dehydrogenase (PDH) in rats with an ED50 value of 0.3 mmol/kg. It reduces increases in plasma levels of lactate and lactate dehydrogenase 1 (LDH-1), markers of ischemic injury, in a dog model of microsphere-induced coronary ischemia when administered at a dose of 0.1 mmol/kg.
WARNING This product is not for human or veterinary use.
Technical Information
- 4-hydroxy-L-Phenylglycine
- p-hydroxy-L-Phenylglycine
- UK 25842
- DMSO: slightly soluble
- PBS (pH 7.2): slightly soluble
Shipping & Storage Information
| SKU | CAYM-11159-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 11159-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 553-63-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |