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Cayman 1-Palmitoyl-2-Hydroxy-Sn-Glycero-3-Pc; Purity- Greater Tha
List Price
$108.00
Your Price
$108.00
Cayman 1-Palmitoyl-2-Hydroxy-Sn-Glycero-3-Pc; Purity- Greater Than Or Equal To 98%; Size- 100 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-10172-100
MFG.PART:
10172-100
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine. It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and phosphorylation of ERK1/2 in human umbilical vein endothelial cells (HUVECs) when used at a concentration of 125 µM. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC potentiates the secretion of IL-6, IL-1β, IL-12, and TNF-α in LPS-stimulated M1 macrophages, but has no effect on CD163, CD206, CD36, or IL-10 in LPS-stimulated M2 macrophages when used at concentrations of 0.3 and 1.0 µM. It increases TGF-β1 production and enhances Foxp3 protein levels in Treg cells in isolated human peripheral blood when used at a concentration of 10 µM. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC enhances neutrophil function, bacterial clearance, and survival in mouse models of sepsis when administered at a dose of 10 mg/kg.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(7R)-4,7-di
CAS Number
17364-16-8
Synonyms
- 1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine
- 1-Hexadecanoyl-sn-glycero-3-Phosphocholine
- 1-Hexadecanoyl-sn-glycerol-3-Phosphorylcholine
- LPC(16:0)
- 16:0 Lyso PC
- 1-Palmitoyl-sn-glycero-3-Phosphocholine
- PC(16:0/0:0)
Molecular Formula
C24H50NO7P
Formula Weight
495.6
Purity
≥98% (9:1 mixture of 1-acyl and 2-acyl)
Formulation
A crystalline solid
Solubility
- PBS (pH 7.2): 2 mg/ml
SMILES
CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OCC[N](C)(C)C
InChi Code
InChI=1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m1/s1
InChi Key
ASWBNKHCZGQVJV-HSZRJFAPSA-N
Side Chain Carbon Sum
16:0
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-10172-100 |
|---|---|
| Featured | No |
| Supplier Part Number | 10172-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 17364-16-8 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |