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Cayman Paf Acetylhydrolase Assay Buffer 2; Size- 1 Ea
List Price
$10.00
Your Price
$10.00
Cayman Paf Acetylhydrolase Assay Buffer 2; Size- 1 Ea; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-760911-1
MFG.PART:
760911-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
(+)-Nutlin-3 is the enantiomer and less active form of the p53-Mdm2 protein-protein interaction inhibitor (–)-nutlin-3 (Item No. ). It inhibits the interaction between p53 and Mdm2 150-fold less potently than (–)-nutlin-3 with an IC50 value of 13.6 µM. (+)-Nutlin-3 has been used as a negative control for the p53-modulating activity of (–)-nutlin-3 in cancer cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4- [[(4R,5S)- 4,5- bis(4- chlorophenyl)- 4,5- dihydro- 2- [4- methoxy- 2- (1- methylethoxy)phenyl]- 1H- imidazol- 1- yl]carbonyl]- 2- piperazinone
CAS Number
675576-97-3
Synonyms
- Nutlin 3b
Molecular Formula
C30H30Cl2N4O4
Formula Weight
581.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 14 mg/ml
- DMSO: 14 mg/ml
- Ethanol: 20 mg/ml
- Ethanol:PBS (pH7.2) (1:7): 0.12 mg/ml
SMILES
ClC1=CC=C([C@H]2[C@@H](C3=CC=C(Cl)C=C3)N=C(C4=CC=C(OC)C=C4OC(C)C)N2C(N5CCN([H])C(C5)=O)=O)C=C1
InChi Code
InChI=1S/C30H30Cl2N4O4/c1-18(2)40-25-16-23(39-3)12-13-24(25)29-34-27(19-4-8-21(31)9-5-19)28(20-6-10-22(32)11-7-20)36(29)30(38)35-15-14-33-26(37)17-35/h4-13,16,18,27-28H,14-15,17H2,1-3H3,(H,33,37)/t27-,28+/m1/s1
InChi Key
BDUHCSBCVGXTJM-IZLXSDGUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-760911-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 760911-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |