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Cayman Tetramethyl Nordihydroguaiaretic Acid; Purity- Greater Tha
List Price
$16.00
Your Price
$16.00
Cayman Tetramethyl Nordihydroguaiaretic Acid; Purity- Greater Than Or Equal To 95%; Size- 50 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-70302-50
MFG.PART:
70302-50
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
tetramethyl Nordihydroguaiaretic acid is a derivative of the lipoxygenase inhibitor nordihydroguaiaretic acid (Item No. 70300).1,2 It inhibits Tat-regulated HIV promoter transactivation in COS-1 cells in a reporter assay with an IC50 value of 11 µM and inhibits the replication of acyclovir-sensitive and -resistant strains of herpes simplex virus (HSV-1) in Vero cells in a reporter assay with IC50 values of 5.6 and 8.9 µM, respectively.1,3 tetramethyl Nordihydroguaiaretic acid (50 µM) induces cell cycle arrest at the G1/G0 phase in A375 melanoma cells and inhibits tumor growth in an A375 mouse xenograft model when administered at a dose of 250 mg/kg.2 tetramethyl Nordihydroguaiaretic acid (166 mg/kg) also reduces tumor growth in a B16 murine melanoma model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
rel-4-[(2R,3S)-
CAS Number
24150-24-1
Synonyms
- EM-1421
- M4N
- Tetrameprocol
- tetramethyl NDGA
- TMNDGA
Molecular Formula
C22H30O4
Formula Weight
358.5
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 2.5 mg/ml
- DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml
- DMSO: 2 mg/ml
- Ethanol: 0.2 mg/ml
λmax
230, 280 nm
SMILES
COc1cc(ccc1OC)CC(C)C(C)Cc1ccc(OC)c(OC)c1
InChi Code
InChI=1S/C22H30O4/c1-15(11-17-7-9-19(23-3)21(13-17)25-5)16(2)12-18-8-10-20(24-4)22(14-18)26-6/h7-10,13-16H,11-12H2,1-6H3/t15-,16+
InChi Key
ORQFDHFZSMXRLM-IYBDPMFKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-70302-50 |
|---|---|
| Featured | No |
| Supplier Part Number | 70302-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 24150-24-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |