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Cayman Blasticidin A; Purity- Greater Than Or Equal To 95%; Size-
Product Description
Free fatty acid receptor 4 (FFAR4/GPR120) is a G protein-coupled receptor expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids., ω-3 Fatty acids, such as docosahexaenoic acid (Item No. ) and eicosapentaenoic acid (Item No. ), initiate FFAR4 signaling, resulting in inhibition of toll-like receptor and TNF-α inflammatory signaling pathways in a β-arrestin2/TAB1 dependent manner. AH 7614 is a selective FFAR4 antagonist (IC50s = 0.079 and 25 µM for human FFAR4 and FFAR1 receptors, respectively). In U2OS osteosarcoma cells expressing the FFAR4 receptor, it has been shown to inhibit intracellular calcium accumulation induced by either linoleic acid or an FFAR4 agonist.
WARNING This product is not for human or veterinary use.
Technical Information
- NSC 31171
- N-xanthen-9-yl-p-Toluenesulfonamide
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml
Shipping & Storage Information
| SKU | CAYM-25519-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 25519-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 100513-53-9 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |