We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn more.
Cayman Teleocidin A1; Purity- Greater Than Or Equal To 98%; Size-
List Price
$351.75
Your Price
$351.75
Cayman Teleocidin A1; Purity- Greater Than Or Equal To 98%; Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25482-1
MFG.PART:
25482-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Teleocidin A1, also known as lyngbyatoxin A, is a fungal metabolite that has been isolated from S. mediocidicus and is the R enantiomer of (S)-teleocidin A. It acts as a tumor promoter, inducing ornithine decarboxylase activity in mouse skin, increasing adhesion of HL-60 human leukemia cells (ED50 = 7 ng/ml), and inducing tumor formation in 87% of mice after 30 weeks when administered at a dose of 3 µg twice per week. Teleocidin A1 also increases the production of prostaglandins and the turnover of choline in HeLa cells when used at concentrations ranging from 6 to 20 ng/ml. It is a substrate for the methyltransferase TleD in Streptomyces where it is converted to teleocidin B.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(2S,5S)-9- [(1R)-1-ethenyl- 1,5-dimethyl- 4-hexen-1-yl]- 1,2,4,5,6,8- hexahydro-5- (hydroxymethyl)- 1-methyl-2-(1- methylethyl)- 3H-pyrrolo [4,3,2-gh]- 1,4-benzo diazonin-3-one
CAS Number
70497-14-2
Synonyms
- Lyngbyatoxin A
Molecular Formula
C27H39N3O2
Formula Weight
437.6
Purity
≥98%
Formulation
A solid
Solubility
- DMF: Soluble
- DMSO: Soluble
- Ethanol: Soluble
- Methanol: Soluble
SMILES
O=C([C@@H](C(C)C)N1C)N[C@H](CO)CC2=CNC3=C([C@](C=C)(C)CC/C=C(C)/C)C=CC1=C32
InChi Code
InChI=1S/C27H39N3O2/c1-8-27(6,13-9-10-17(2)3)21-11-12-22-23-19(15-28-24(21)23)14-20(16-31)29-26(32)25(18(4)5)30(22)7/h8,10-12,15,18,20,25,28,31H,1,9,13-14,16H2,2-7H3,(H,29,32)/t20-,25+,27-/m0/s1
InChi Key
KISDGNGREAJPQR-FESMNKHTSA-N
Origin
Bacterium/Streptomyces
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25482-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 25482-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 70497-14-2 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |