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Cayman 1,2-Dilinoleoyl-Sn-Glycerol; Purity- Greater Than Or Equal
List Price
$44.00
Your Price
$44.00
Cayman 1,2-Dilinoleoyl-Sn-Glycerol; Purity- Greater Than Or Equal To 95%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25422-10
MFG.PART:
25422-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
c-Jun N-terminal kinases (JNKs) are MAP kinase family members that become highly activated after cells are exposed to stress conditions and are poorly activated by exposure to growth factors or mitogens. CC-401 is a potent inhibitor of all three JNK isoforms (Ki values range from 25 to 50 nM)., It has at least 40-fold selectivity for JNK compared with other related kinases. CC-401 is bioavailable when delivered by gavage, blocking JNK signaling and renal fibrosis in a rat obstructed kidney model. It also has been shown to decrease hepatic necrosis and apoptosis after orthotopic liver transplantation and prevent acute renal failure following ischemia/reperfusion associated with renal transplantation in rats.,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-[3-[2-(1-
CAS Number
395104-30-0
Molecular Formula
C22H24N6O
Formula Weight
388.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- PBS (pH 7.2): 2 mg/ml
λmax
217, 240, 315 nm
SMILES
C1(C2=NN=CN2)=CC=C3C(C(C4=CC=CC(OCCN5CCCCC5)=C4)=NN3)=C1
InChi Code
InChI=1S/C22H24N6O/c1-2-9-28(10-3-1)11-12-29-18-6-4-5-16(13-18)21-19-14-17(22-23-15-24-27-22)7-8-20(19)25-26-21/h4-8,13-15H,1-3,9-12H2,(H,25,26)(H,23,24,27)
InChi Key
XDJCLCLBSGGNKS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25422-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 25422-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 24529-89-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |