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Cayman Nonivamide; Purity- Greater Than Or Equal To 98%; Size- 10
List Price
$172.00
Your Price
$172.00
Cayman Nonivamide; Purity- Greater Than Or Equal To 98%; Size- 10 G; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25328-10
MFG.PART:
25328-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Amenamevir is an antiviral inhibitor of herpes simplex virus 1 (HSV-1) helicase-primase complex activity. It inhibits recombinant HSV-1 helicase with an IC50 value of 0.078 μM and recombinant HSV-1 primase when used at concentrations greater than or equal to 0.03 μM. Amenamevir inhibits replication of varicella-zoster virus (VZV), HSV-1, and HSV-2 in human embryonic fibroblast (HEF) cells (EC50s = 0.047, 0.036, and 0.028 μM, respectively) and is not cytotoxic to HEF cells with a 50% cytotoxic concentration (CC50) of greater than 30 μM. Amenamevir also inhibits replication of clinical VZV isolates in HEF cells (EC50s = 0.038-0.10 μM). In vivo, it increases survival of cutaneously HSV-1-infected mice in a zosteriform-spread model of progressive HSV-1 infection (ED50 = 1.9 mg/kg twice per day).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(2,6-
CAS Number
841301-32-4
Synonyms
- ASP2151
Molecular Formula
C24H26N4O5S
Formula Weight
482.6
Purity
≥98%
Formulation
A solid
Solubility
- DMF: 2 mg/ml
- DMF:PBS (pH 7.2) (1:20): 0.04 mg/mL
- DMSO: 10 mg/ml
- Ethanol: Partially soluble
λmax
275 nm
SMILES
O=S1(CCC(C(N(C2=C(C)C=CC=C2C)CC(NC3=CC=C(C4=NOC=N4)C=C3)=O)=O)CC1)=O
InChi Code
InChI=1S/C24H26N4O5S/c1-16-4-3-5-17(2)22(16)28(24(30)19-10-12-34(31,32)13-11-19)14-21(29)26-20-8-6-18(7-9-20)23-25-15-33-27-23/h3-9,15,19H,10-14H2,1-2H3,(H,26,29)
InChi Key
MNHNIVNAFBSLLX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25328-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 25328-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | Y |
| CAS Number | 2444-46-4 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |