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Cayman Ly3200882; Purity- Greater Than Or Equal To 95%; Size- 5 M
List Price
$161.00
Your Price
$161.00
Cayman Ly3200882; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25276-5
MFG.PART:
25276-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
G protein-regulated inwardly rectifying potassium (GIRK1-4) channels are a family of Kir3.1-Kir3.4 ion channels that modulate cell excitability. The four different GIRK subunits are composed in different homo- and heterotetrameric combinations, which are expressed with regional specificity throughout the central nervous system and in the periphery. ML-297 is a selective GIRK1/2 activator (EC50s = 0.16 and 1.8 μM for GIRK1/2 and GIRK1/4, respectively, and is completely inactive at GIRK2/3)., In two different mouse models of epilepsy, ML-297 at 60 mg/kg was shown to delay seizure onset and to prevent convulsions.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(3,4-
CAS Number
1443246-62-5
Synonyms
- CID-56642816
- VU0456810
Molecular Formula
C17H14F2N4O
Formula Weight
328.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 20 mg/ml
- PBS (pH 7.2): 10 mg/ml
λmax
244 nm
SMILES
O=C(NC1=CC(F)=C(F)C=C1)NC2=CC(C)=NN2C3=CC=CC=C3
InChi Code
InChI=1S/C17H14F2N4O/c1-11-9-16(23(22-11)13-5-3-2-4-6-13)21-17(24)20-12-7-8-14(18)15(19)10-12/h2-10H,1H3,(H2,20,21,24)
InChi Key
IEKSMUSSYJUQMY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25276-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 25276-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1898283-02-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |