Cayman Salbutamol-D9; Purity- Greater Than Or Equal To 99% Deuter

List Price $93.00 Your Price $93.00
Cayman Salbutamol-D9; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D9); Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25234-500
MFG.PART: 25234-500
UNSPSC: 12352200
Manufacturer: Cayman
Product Description

Empagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor (IC50 = 3.1 nM for the human transporter). It is selective for SGLT2 over SGLT1, -4, -5, and -6 (IC50s = 8.3, 11, 1.1, and 2 µM, respectively). Dietary administration of empagliflozin (0.03% for 10 weeks) reduces non-fasting blood glucose levels, as well as aortic superoxide levels and cardiac interstitial fibrosis, in db/db mice. It also decreases the severity of glomerulosclerosis, as well as reduces the escape latency in the Morris water maze, in the same model. Formulations containing empagliflozin have been used in the treatment of type 2 diabetes.

WARNING This product is not for human or veterinary use.

Technical Information
Formal Name
(1S)-1,5-anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol
CAS Number
864070-44-0
Synonyms
  • BI 10773
Molecular Formula
C23H27ClO7
Formula Weight
450.9
Purity
≥98%
Formulation
A crystalline solid
Solubility
  • DMF: 30 mg/ml
  • DMSO: 30 mg/ml
  • Ethanol: 30 mg/ml
  • Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
224 nm
SMILES
ClC(C=CC([C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1)=C2)=C2CC3=CC=C(O[C@@H]4COCC4)C=C3
InChi Code
InChI=1S/C23H27ClO7/c24-18-6-3-14(23-22(28)21(27)20(26)19(11-25)31-23)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21-,22+,23-/m0/s1
InChi Key
OBWASQILIWPZMG-QZMOQZSNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
More Information
SKU CAYM-25234-500
Featured No
Supplier Part Number 25234-500
UM EA
UNSPSC 12352200
Manufacturer Name Cayman
MSDS URL Click here
Temperature -20
Refrigerated-Frozen Refrigerated
CountryOfOrigin Canada
ProductLine CAYM
Qty 1
MinOrderQty 1
Weight 7.000000
Lead Time 2
Hazardous N
CAS Number 1173021-73-2
Energy Star No
Green No
ACT Ecolabel No
Controlled N
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