Cayman (В±)-Efavirenz-D5; Purity- Greater Than Or Equal To 99% De

Sulfadimethoxine is a sulfonamide antibiotic that is active against Gram-negative and Gram-positive bacteria and other microorganisms. It inhibits recombinant P. carinii dihydropteroate synthase (DHPS; IC₅₀ = 25 nM), an enzyme required for folate biosynthesis, in a cell-free assay. Sulfadimethoxine is active against S. aureus, S. pneumoniae, K. pneumoniae, and E. coli in a disc assay. It is also active against C. spiroforme isolates from rabbits (MIC₉₀ = 256 μg/ml) and certain M. bovoculi isolates from keratoconjunctivitis infections in cows (MIC₅₀ = ≤256 μg/ml).^, Sulfadimethoxine is efficacious against S. pneumoniae, K. pneumoniae, and E. coli systemic infections in mice with 50% curative dose (CD₅₀) values of 79.7, 2.7, and 12.2 mg/kg, respectively. It is also efficacious against H. capsulatum systemic fungal infections in mice (CD₅₀ = 300 mg/kg).

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