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Cayman Valsartan-D9; Purity- Greater Than Or Equal To 99% Deutera
List Price
$364.00
Your Price
$364.00
Cayman Valsartan-D9; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D9); Size- 1 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25226-1
MFG.PART:
25226-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Valsartan-d9 is intended for use as an internal standard for the quantification of valsartan (Item No. ) by GC- or LC-MS. Valsartan is a nonpeptide antagonist of the angiotensin II type 1 (AT1) receptor (IC50 = 2.7 nM). It is 20,000-fold selective for AT1 over AT2 and, unlike some other AT receptor antagonists, does not alter peroxisome proliferator-activated receptor γ (PPARγ) activity in vitro. In vivo, valsartan (30 mg/kg) increases cardiac output and reduces left ventricular fibrosis in a model of heart failure with reduced ejection fraction in mice with streptozotocin-induced diabetes. Formulations containing valsartan have been used in the treatment of hypertension and heart failure.,,
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(1-oxopentyl-
CAS Number
1089736-73-1
Synonyms
- CGP 48933-d9
Molecular Formula
C24H20D9N5O3
Formula Weight
444.6
Purity
≥99% deuterated forms (d1-d9)
Formulation
A solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 30 mg/ml
SMILES
O=C(C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])N([C@@](C(O)=O)([H])C(C)C)CC1=CC=C(C2=CC=CC=C2C3=NNN=N3)C=C1
InChi Code
InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1/i1D3,4D2,5D2,10D2
InChi Key
ACWBQPMHZXGDFX-KDDXQTGLSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25226-1 |
|---|---|
| Featured | No |
| Supplier Part Number | 25226-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1089736-73-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |