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Cayman Procyanidin A2; Purity- Greater Than Or Equal To 95%; Size
List Price
$180.00
Your Price
$180.00
Cayman Procyanidin A2; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25200-5
MFG.PART:
25200-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
CHM-1 is an inhibitor of tubulin polymerization (IC50 = 0.68 µM) with anticancer activity. It inhibits colchicine (Item No. ) tubulin binding by 39% when used at a concentration of 5 µM. CHM-1 inhibits the growth of K562, NCI H226, HCT116, OVCAR-3, RXF 393L, SK-MEL-5, SF-268, and SF-295 cancer cells (mean GI50 = 130 nM). It induces apoptosis in HA22T hepatocellular carcinoma cells in a concentration-dependent manner. CHM-1 (10 mg/kg) reduces tumor volume and increases survival in an HA22T mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-(2-fluoro
CAS Number
154554-41-3
Synonyms
- NSC 656158
Molecular Formula
C16H10FNO3
Formula Weight
283.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: soluble
λmax
228, 256, 326 nm
SMILES
O=C(C=C(C1=C(F)C=CC=C1)N2)C3=C2C=C(OCO4)C4=C3
InChi Code
InChI=1S/C16H10FNO3/c17-11-4-2-1-3-9(11)12-6-14(19)10-5-15-16(21-8-20-15)7-13(10)18-12/h1-7H,8H2,(H,18,19)
InChi Key
ZMYDAPJHGNEFGQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25200-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 25200-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 41743-41-3 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |