Cayman Fin56; Purity- Greater Than Or Equal To 98%; Size- 10 Mg;

List Price $120.00 Your Price $120.00
Cayman Fin56; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25180-10
MFG.PART: 25180-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description

FIN56 is an inducer of ferroptosis and a derivative of CIL56 (Item No. ). It selectively induces ferroptosis in BJ cells overexpressing oncogenic HRASG12V via acetyl-CoA carboxylase-dependent reduction in expression of GPX4 protein. This effect is reversed by the ferroptosis inhibitors deferoxamine (Item No. ) and α-tocopherol as well as overexpression of the fusion protein GFP-GPX4. FIN56 also binds to and activates squalene synthase in a GPX4 degradation-independent manner.

WARNING This product is not for human or veterinary use.

Technical Information
Formal Name
N2,N7-dicyclohexyl-9-(hydroxyimino)-9H-fluorene-2,7-disulfonamide
CAS Number
1083162-61-1
Molecular Formula
C25H31N3O5S2
Formula Weight
517.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
  • DMF: 30 mg/ml
  • DMSO: 30 mg/ml
λmax
223, 267, 305 nm
SMILES
O/N=C1C2=C(C=CC(S(NC3CCCCC3)(=O)=O)=C2)C4=C/1C=C(S(NC5CCCCC5)(=O)=O)C=C4
InChi Code
InChI=1S/C25H31N3O5S2/c29-26-25-23-15-19(34(30,31)27-17-7-3-1-4-8-17)11-13-21(23)22-14-12-20(16-24(22)25)35(32,33)28-18-9-5-2-6-10-18/h11-18,27-29H,1-10H2
InChi Key
JLCFMMIWBSZOIS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
More Information
SKU CAYM-25180-10
Featured No
Supplier Part Number 25180-10
UM EA
UNSPSC 12352200
Manufacturer Name Cayman
MSDS URL Click here
Temperature -20
Refrigerated-Frozen Refrigerated
CountryOfOrigin China
ProductLine CAYM
Qty 1
MinOrderQty 1
Weight 7.000000
Lead Time 2
Hazardous N
CAS Number 1083162-61-1
Energy Star No
Green No
ACT Ecolabel No
Controlled N
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