Cayman Ginkgetin; Purity- Greater Than Or Equal To 98%; Size- 1 M

Ginkgetin is a biflavonoid that has been isolated from G. biloba and has diverse biological activities, including pro-apoptotic, antiproliferative, anti-inflammatory, anti-atherosclerosis, and neuroprotective properties.^,,, It inhibits the proliferation of OVCAR-3 ovarian and HeLa cervical cancer cells (EC₅₀s = 3 and 5.2 μg/ml, respectively) and induces apoptosis and caspase-3 cleavage in OVCAR-3 cells when used at a concentration of 3 μg/ml. Topical ginkgetin (20 μg/ear) reduces ear edema and prostaglandin E₂ (PGE₂; Item No. ) levels in a mouse model of chronic skin inflammation induced by phorbol 12-myristate 13-acetate (PMA; Item No. ). It decreases the thickness of the intima-media and lipid plaque deposition in the thoracic aorta in a rat model of high-fat diet-induced atherosclerosis when administered at a dose of 100 mg/kg. Ginkgetin (0.8 mg/kg per day) improves sensorimotor coordination and increases the time spent on a rotating bar in a mouse model of Parkinsons disease induced by MPTP.

WARNING This product is not for human or veterinary use.