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Cayman Cryptochlorogenic Acid; Purity- Greater Than Or Equal To 9
List Price
$146.00
Your Price
$146.00
Cayman Cryptochlorogenic Acid; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25098-10
MFG.PART:
25098-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Pyrvinium is an anthelmintic and anticancer agent., Dietary administration of pyrvinium reduces worm burden in mouse models of N. dubius, S. obvelata, or A. tetraptera infection (EC50s = 292, 4, and 17 ppm, respectively) but is lethal to mice at higher concentrations (LC50 = 600 ppm). Pyrvinium (1 μg/ml) induces cytotoxicity in PANC-1 cells cultured in glucose-deficient medium but not serum- or amino acid-deficient medium or complete medium. It reduces tumor growth in a PANC-1 mouse xenograft model when administered at a dose of 100 μg/mouse per day. Pyrvinium (10 nM) also binds to and activates casein kinase 1α (CK1α). It inhibits Wnt signaling (EC50 = ~10 nM in a reporter assay) in a CK1α-dependent manner. Formulations containing pyrvinium were previously used in the treatment of pinworm infections.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4,4′-methylhydroxy-2-naphthalenecarboxylate] 6-(dimethylamino)-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methyl-quinolinium
CAS Number
3546-41-6
Synonyms
- NSC 223622
Molecular Formula
C26H28N3 • 1/2C23H14O6
Formula Weight
575.7
Purity
≥95%
Formulation
A solid
Solubility
- DMF: 1 mg/ml
- DMSO: 1 mg/ml
- DMSO:PBS (pH 7.2) (1:2): 0.3 mg/ml
λmax
236, 357, 506 nm
SMILES
C[N+]1=C2C=CC(N(C)C)=CC2=CC=C1/C=C/C3=C(C)N(C4=CC=CC=C4)C(C)=C3.O=C(C5=CC6=C(C(CC7=C8C(C=CC=C8)=CC(C([O-])=O)=C7O)=C5O)C=CC=C6)[O-].C[N+]9=C%10C=CC(N(C)C)=CC%10=CC=C9/C=C/C%11=C(C)N(C%12=CC=CC=C%12)C(C)=C%11
InChi Code
InChI=1S/2C26H28N3.C23H16O6/c2*1-19-17-21(20(2)29(19)24-9-7-6-8-10-24)11-13-23-14-12-22-18-25(27(3)4)15-16-26(22)28(23)5;24-20-16(14-7-3-1-5-12(14)9-18(20)22(26)27)11-17-15-8-4-2-6-13(15)10-19(21(17)25)23(28)29/h2*6-18H,1-5H3;1-10,24-25H,11H2,(H,26,27)(H,28,29)/q2*+1;/p-2
InChi Key
OOPDAHSJBRZRPH-UHFFFAOYSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25098-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 25098-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 905-99-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |