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Cayman Caftaric Acid; Purity- Greater Than Or Equal To 98%; Size-
List Price
$356.00
Your Price
$356.00
Cayman Caftaric Acid; Purity- Greater Than Or Equal To 98%; Size- 10 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25090-10
MFG.PART:
25090-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
SMYD2 is a lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53 and retinoblastoma-associated protein., LLY-507 is a cell-active, small molecule inhibitor of SMYD2 (IC50 = 15 nM). It has been shown to inhibit p53 lysine370 monomethylation in KYSE-150 esophageal squamous cell carcinoma cells stably expressing SMYD2 with an IC50 value of 0.6 µM. LLY-507 is >100-fold selective for SMYD2 over a panel of 27 protein methyltransferases and non-methyltransferase targets. See the website for more information.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-cyano-2- [4-[2-(3-methyl- 1H-indol-1-yl)ethyl] -1-piperazinyl]-N- [3-(1-pyrrolidinyl)propyl] -[1,1-biphenyl]-3- carboxamide
CAS Number
1793053-37-8
Molecular Formula
C36H42N6O
Formula Weight
574.8
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/ml
- DMSO: 30 mg/ml
- Ethanol: 25 mg/ml
λmax
227 nm
SMILES
N#CC1=CC(C(NCCCN2CCCC2)=O)=CC(C3=CC=CC=C3N4CCN(CCN5C=C(C)C6=C5C=CC=C6)CC4)=C1
InChi Code
InChI=1S/C36H42N6O/c1-28-27-42(34-11-4-2-9-32(28)34)22-19-40-17-20-41(21-18-40)35-12-5-3-10-33(35)30-23-29(26-37)24-31(25-30)36(43)38-13-8-16-39-14-6-7-15-39/h2-5,9-12,23-25,27H,6-8,13-22H2,1H3,(H,38,43)
InChi Key
PNYRDVBFYVDJJI-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25090-10 |
|---|---|
| Featured | No |
| Supplier Part Number | 25090-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 67879-58-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |