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Cayman Benzomalvin B; Purity- Greater Than Or Equal To 95%; Size-
List Price
$743.40
Your Price
$743.40
Cayman Benzomalvin B; Purity- Greater Than Or Equal To 95%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25088-5
MFG.PART:
25088-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Tyro3, Axl, and Mer are members of the TAM family of receptor tyrosine kinases that have signaling roles in normal and malignant cells. UNC2250 is an inhibitor of Mer kinase activity, blocking the steady-state phosphorylation of endogenous Mer in 697 B-ALL cells with an IC50 value of 9.8 nM. It is selective for Mer over a panel of both tyrosine and serine-threonine kinases, including Tyro3 and Axl. UNC2250 also inhibits ligand-dependent phosphorylation of a chimeric EGFR-Mer protein and blocks colony formation in soft agar cultures of BT-12 rhabdoid tumor and Colo699 NSCLC cell lines. UNC2250 displays good pharmacokinetic properties in mice following intravenous or oral administration.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
trans-4-[[2-
CAS Number
1493694-70-4
Molecular Formula
C24H36N6O2
Formula Weight
440.6
Purity
≥98%
Formulation
A crystalline solid
λmax
232, 274, 332 nm
SMILES
CCCCNC1=NC=C(C2=NC=C(CN3CCOCC3)C=C2)C(N[C@@H]4CC[C@@H](O)CC4)=N1
InChi Code
InChI=1S/C24H36N6O2/c1-2-3-10-25-24-27-16-21(23(29-24)28-19-5-7-20(31)8-6-19)22-9-4-18(15-26-22)17-30-11-13-32-14-12-30/h4,9,15-16,19-20,31H,2-3,5-8,10-14,17H2,1H3,(H2,25,27,28,29)/t19-,20-
InChi Key
HSYSSKFCQHXOBP-MXVIHJGJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25088-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 25088-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 157047-97-7 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |
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