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Cayman Isokotanin B; Purity- Greater Than Or Equal To 95%; Size-
List Price
$585.90
Your Price
$585.90
Cayman Isokotanin B; Purity- Greater Than Or Equal To 95%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25082-2.5
MFG.PART:
25082-2.5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Foretinib is a broad-spectrum tyrosine kinase (TK) inhibitor that targets members of the HGF and VEGF receptor TK families, as well as KIT, Flt-3, PDGFRβ, and Tie-2, at nanomolar concentrations., It blocks HGF-induced Met phosphorylation and VEGF-induced ERK phosphorylation, preventing HGF-induced responses in tumor cells and HGV/VEGF-induced responses in endothelial cells., Foretinib is functional in vivo, reducing tumor burden in an experimental model of lung metastasis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[3-fluoro-4-
CAS Number
849217-64-7
Synonyms
- GSK1363089
- XL880
Molecular Formula
C34H34F2N4O6
Formula Weight
632.7
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 16 mg/ml
- Ethanol: 25 mg/ml
- Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
λmax
242 nm
SMILES
COC(C=C(C(OC1=CC=C(NC(C2(CC2)C(NC3=CC=C(F)C=C3)=O)=O)C=C1F)=CC=N4)C4=C5)=C5OCCCN6CCOCC6
InChi Code
InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)
InChi Key
CXQHYVUVSFXTMY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25082-2.5 |
|---|---|
| Featured | No |
| Supplier Part Number | 25082-2.5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 154160-09-5 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |