Cayman Betamangostin; Purity- Greater Than Or Equal To 95%; Siz

β-Mangostin is a xanthone originally isolated from G. mangostana with diverse biological activites.^1,2,3,4,5,6 It inhibits growth of methicillin-resistant S. aureus (MRSA) and methicillin-susceptible S. aureus (MSSA; MICs = 6.25-12.5 and 6.25-25 μg/ml, respectively), P. falciparum (IC₅₀ = 3 μg/ml), and M. tuberculosis (MIC = 6.25 μg/ml).^1,2,3 β-Mangostin inhibits fatty acid synthase (FASN) with an IC₅₀ value of 24.83 μM.⁴ It induces cell cycle arrest at the G₂/M phase and intrinsic and mitochondrial apoptosis in MCF-7 breast cancer cells.⁵ β-Mangostin also inhibits LPS-induced nitric oxide and prostaglandin E₂ (PGE₂; Item No. 14010) production in RAW264.7 cells and reduces neutrophil infiltration and TNF-α and IL-1β production in a mouse model of carrageenan-induced peritonitis.⁶

WARNING This product is not for human or veterinary use.