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Cayman Loratadine-D5; Purity- Greater Than Or Equal To 99% Deuter
List Price
$117.00
Your Price
$117.00
Cayman Loratadine-D5; Purity- Greater Than Or Equal To 99% Deuterated Forms (D1-D5); Size- 500 Micrograms; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25040-500
MFG.PART:
25040-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Loratadine-d5 is intended for use as an internal standard for the quantification of loratadine (Item No. 15625) by GC- or LC-MS. Loratadine is a non-sedating antihistamine that acts as a selective inverse agonist of peripheral histamine H1 receptors (Ki = 35 nM).1,2,3 It has been shown to inhibit the release of leukotriene C4 (IC50 = 8 µM) and histamine (IC50 = 11 µM) from rodent mast cells and to inhibit allergic bronchospasm in guinea pigs with an ED50 value of 0.40 mg/kg.4 Formulations containing loratadine have been used in the treatment of allergic rhinitis and chronic idiopathic urticaria.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-(8-chloro-
CAS Number
1020719-57-6
Molecular Formula
C22H18ClD5N2O2
Formula Weight
387.9
Purity
≥99% deuterated forms (d1-d5)
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 25 mg/ml
- Ethanol: 30 mg/ml
SMILES
ClC(C=C1)=CC(CC([2H])([2H])C2=C/3N=C([2H])C([2H])=C2[2H])=C1C3=C4CCN(C(OCC)=O)CC/4
InChi Code
InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3/i3D,4D,5D2,11D
InChi Key
JCCNYMKQOSZNPW-XFHCPBGCSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25040-500 |
|---|---|
| Featured | No |
| Supplier Part Number | 25040-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1020719-57-6 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |
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