Cayman Cinacalcet-D3 (Hydrochloride); Purity- Greater Than Or Equ

BIMU 8 is an agonist of the serotonin (5-HT) receptor subtype 5-HT₄ (K_i = 69 nM). It also binds 5-HT₃ receptors (K_i = 0.36 nM). It stimulates cAMP formation in primary mouse embryonic colliculi neurons with an EC₅₀ value of 72 nM. BIMU 8 (30, 40, and 60 nmol/animal, i.c.v.) induces acetylcholine release in the rat frontal cortex. It increases postprandial antral and colonic motility in conscious dogs when administered at doses of 0.1, 0.3, and 1 mg/kg. BIMU 8 (20 mg/kg, i.p.) also increases the latency to withdraw in the paw pressure test in rats.

WARNING This product is not for human or veterinary use.