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Cayman Eos200271; Purity- Greater Than Or Equal To 98%; Size- 25
List Price
$90.00
Your Price
$90.00
Cayman Eos200271; Purity- Greater Than Or Equal To 98%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25003-25
MFG.PART:
25003-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
EOS200271 is an inhibitor of indoleamine 2,3-dioxygenase 1 (IDO-1; IC50 = 0.15 µM for the human enzyme).1 It is selective for IDO-1 over IDO-2 up to a concentration of 200 µM for the human recombinant enzymes. EOS200271 inhibits IDO-1-mediated production of kynurenine induced by IFN-γ in HeLa cells (IC50 = 1.8 µM) and by LPS and IFN-γ in THP-1 cells and human-derived whole blood ex vivo (IC50s = 1.7 and 4.7 µM, respectively).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-(5-fluoro-
CAS Number
198474-05-4
Synonyms
- PF-06840003
Molecular Formula
C12H9FN2O2
Formula Weight
232.2
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
λmax
221, 287 nm
SMILES
FC1=CC=C2C(C(C3CC(NC3=O)=O)=CN2)=C1
InChi Code
InChI=1S/C12H9FN2O2/c13-6-1-2-10-7(3-6)9(5-14-10)8-4-11(16)15-12(8)17/h1-3,5,8,14H,4H2,(H,15,16,17)
InChi Key
MXKLDYKORJEOPR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25003-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 25003-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 198474-05-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |