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Cayman Aem1; Purity- Greater Than Or Equal To 98%; Size- 5 Mg
List Price
$100.00
Your Price
$100.00
Cayman Aem1; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18321-5
MFG.PART:
18321-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
NUC-1031 is a prodrug form of the anticancer nucleoside analog gemcitabine (Item No. )., NUC-1031 is more lipophilic than gemcitabine and enters cells through passive diffusion. It inhibits the growth of L1210, CEM, MP-2, and BxPC-3 cancer cells in vitro (IC50 = 35, 30, 60, and 40 nM, respectively). NUC-1031 (0.076 mmol/kg) reduces tumor growth in Mia-PaCa-2 and BxPC-3 mouse xenograft models, which are partially responsive and resistant to gemcitabine, respectively.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(2-deoxy-
CAS Number
840506-29-8
Molecular Formula
C25H27F2N4O8P
Formula Weight
580.5
Purity
≥98% (mixture of diastereomers)
Formulation
A crystalline solid
Solubility
- DMF: 12 mg/mL
- DMSO: 14 mg/mL
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL
- Ethanol: 10 mg/mL
λmax
245 nm
SMILES
O[C@H]1C(F)(F)[C@H](N2C(N=C(N)C=C2)=O)O[C@@H]1COP(N[C@@H](C)C(OCC3=CC=CC=C3)=O)(OC4=CC=CC=C4)=O
InChi Code
InChI=1S/C25H27F2N4O8P/c1-16(22(33)36-14-17-8-4-2-5-9-17)30-40(35,39-18-10-6-3-7-11-18)37-15-19-21(32)25(26,27)23(38-19)31-13-12-20(28)29-24(31)34/h2-13,16,19,21,23,32H,14-15H2,1H3,(H,30,35)(H2,28,29,34)/t16-,19+,21+,23+,40?/m0/s1
InChi Key
NHTKGYOMICWFQZ-KKQYNPQSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18321-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 18321-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 1030123-90-0 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |
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