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Cayman Ly315920; Purity- Greater Than Or Equal To 95%; Size- 25 M
List Price
$379.00
Your Price
$379.00
Cayman Ly315920; Purity- Greater Than Or Equal To 95%; Size- 25 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-18267-25
MFG.PART:
18267-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
LY315920 is an inhibitor of human group IIA (hGIIA) secretory phospholipase A2 (sPLA2; IC50 = 9 nM).1 It also potently inhibits human GIIE and GX isoforms, as well as the corresponding mouse isoforms, but poorly inhibits other PLA2 enzymes.1,2,3,4 LY315920 inhibits sPLA2-induced release of thromboxane A2 from isolated guinea pig lung bronchoalveolar lavage cells (IC50 = 0.79 µM).2 Intravenous or oral administration of LY315920 to transgenic mice expressing human sPLA2 inhibits serum sPLA2 activity in a dose-related manner over four hours.2
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-
CAS Number
172732-68-2
Synonyms
- Varespladib
Molecular Formula
C21H20N2O5
Formula Weight
380.4
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 2 mg/ml
- DMSO: 3 mg/ml
- DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
λmax
217, 256, 331 nm
SMILES
O=C(O)COC1=C2C(N(CC3=CC=CC=C3)C(CC)=C2C(C(N)=O)=O)=CC=C1
InChi Code
InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)
InChi Key
BHLXTPHDSZUFHR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-18267-25 |
|---|---|
| Featured | No |
| Supplier Part Number | 18267-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer Name | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 172732-68-2 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |
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